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Pain is the most common reason patients seek medical attention and pain relief has been put forward as an ethical Gays in the Columbia of clinicians and a fundamental human right. However, pain management is challenging because the pathophysiology of pain is complex and not completely understood. Widely used analgesics such as nonsteroidal anti-inflammatory drugs NSAIDs and paracetamol acetaminophen have been associated with adverse events.

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Tramadol/paracetamol fixed-dose combination in the treatment of moderate to severe pain

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